{"id":56800,"date":"2026-09-11T15:39:00","date_gmt":"2026-09-11T15:39:00","guid":{"rendered":"https:\/\/noti-america.com\/site\/venezuela\/?p=56800"},"modified":"2026-09-11T15:39:00","modified_gmt":"2026-09-11T15:39:00","slug":"desvelan-mecanismo-que-hace-que-el-sistema-inmunitario-ayude-al-crecimiento-de-un-tumor","status":"publish","type":"post","link":"https:\/\/noti-america.com\/site\/venezuela\/2026\/09\/11\/desvelan-mecanismo-que-hace-que-el-sistema-inmunitario-ayude-al-crecimiento-de-un-tumor\/","title":{"rendered":"Desvelan mecanismo que hace que el sistema inmunitario ayude al crecimiento de un tumor"},"content":{"rendered":"<p>NOTI-AMERICA.COM | VENEZUELA<\/p>\n<p style=\"text-align: justify\">En las \u00faltimas d\u00e9cadas, la oncolog\u00eda moderna ha desarrollado grandes avances como la inmunoterapia, que aprovecha las propias c\u00e9lulas inmunitarias del cuerpo para combatir el c\u00e1ncer, pero todav\u00eda quedan muchas inc\u00f3gnitas por resolver.<\/p>\n<p style=\"text-align: justify\">Para los onc\u00f3logos, una de las m\u00e1s importantes era averiguar por qu\u00e9 las prote\u00ednas defensivas (interferones) que activan el sistema inmunitario para destruir el c\u00e1ncer, acaban ayudando al tumor a crecer cuando permanecen activas durante demasiado tiempo.Un equipo del Instituto Salk, en La Joya, California, ha descubierto el mecanismo que lo hace posible.<\/p>\n<p style=\"text-align: justify\">La clave de esta transici\u00f3n biol\u00f3gica est\u00e1 en las mitocondrias, las estructuras encargadas de suministrar energ\u00eda a las c\u00e9lulas. Los detalles del estudio se publican este jueves en la revista Science.<\/p>\n<p style=\"text-align: justify\">El laboratorio de Shadel descubri\u00f3 que la exposici\u00f3n cr\u00f3nica a estas mol\u00e9uclas altera el funcionamiento de las c\u00e9lulas del tumor porque en lugar de debilitarlas, este estr\u00e9s continuo hace que el material gen\u00e9tico de las mitocondrias (ADNmt) se filtre en el interior de la c\u00e9lula.<\/p>\n<p style=\"text-align: justify\">El estudio no solo resuelve un enigma fundamental de la biolog\u00eda del c\u00e1ncer, sino que ofrece una soluci\u00f3n pr\u00e1ctica para uno de los mayores obst\u00e1culos de la medicina actual: la resistencia a los f\u00e1rmacos inmunoterap\u00e9uticos (como los tratamientos anti-PD1 que son de los m\u00e1s utilizados).<\/p>\n<p style=\"text-align: justify\">Los hallazgos demuestran su potencial para la traslaci\u00f3n cl\u00ednica en el futuro, ofreciendo una posible v\u00eda para mantener el ataque del sistema inmunitario contra el c\u00e1ncer y una esperanza en casos de resistencia a la inmunoterapia.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>NOTI-AMERICA.COM | VENEZUELA En las \u00faltimas d\u00e9cadas, la oncolog\u00eda moderna ha desarrollado grandes avances como la inmunoterapia, que aprovecha las propias c\u00e9lulas inmunitarias del cuerpo para combatir el c\u00e1ncer, pero todav\u00eda quedan muchas inc\u00f3gnitas&#46;&#46;&#46;<\/p>\n","protected":false},"author":133,"featured_media":56801,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":{"twitter_242054905_242054905":""},"rop_publish_now_history":[],"rop_publish_now_status":"pending","_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[13],"tags":[],"class_list":["post-56800","post","type-post","status-publish","format-image","has-post-thumbnail","hentry","category-vida-y-salud","post_format-post-format-image"],"acf":[],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.9 (Yoast SEO v27.2) - 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