{"id":97400,"date":"2026-10-22T17:32:13","date_gmt":"2026-10-22T21:32:13","guid":{"rendered":"https:\/\/noti-america.com\/site\/principal\/?p=97400"},"modified":"2026-10-22T17:32:13","modified_gmt":"2026-10-22T21:32:13","slug":"cientificos-descifran-la-estructura-molecular-del-hantavirus-andino-y-abren-la-via-para-nuevos-antivirales","status":"publish","type":"post","link":"https:\/\/noti-america.com\/site\/principal\/2026\/10\/22\/cientificos-descifran-la-estructura-molecular-del-hantavirus-andino-y-abren-la-via-para-nuevos-antivirales\/","title":{"rendered":"Cient\u00edficos descifran la estructura molecular del hantavir\u00fcs andino y abren la v\u00eda para nuevos antivirales"},"content":{"rendered":"<p>NOTI-AMERICA.COM | CHILE<\/p>\n<p style=\"text-align: justify\">Un equipo multidisciplinario de cient\u00edficos del Albert Einstein College of Medicine,\u00a0el Institut Pasteur y LSU Health Shreveport logr\u00f3 descifrar la estructura molecular mediante la cual el hantavir\u00fcs andino se adhiere a las c\u00e9lulas humanas para iniciar la infecc\u00ef\u00f3n.<\/p>\n<p style=\"text-align: justify\">Los hallazgos,\u00a0publicados en la revista\u00a0Nature,\u00a0identificaron el punto vulnerable del pat\u00f3geno end\u00e9mic\u00f6 de regiones de Argentina y Chile,\u00a0abriendo la v\u00eda para el desarrollo de tratamientos antivirales y terapias dirigidas.<\/p>\n<p style=\"text-align: justify\">A trav\u00e9s de microscop\u00eda crioelectr\u00f3nica y modelos guiados por inteligencia artificial,\u00a0los investigadores determinaron que la prote\u00edna de la esp\u00edcula del virus requiere una configuraci\u00f3n cuadrada para acoplarse al receptor celular espec\u00edfico PCDH1.\u00a0El estudio tambi\u00e9n revel\u00f3 el mecanismo por el cual el vir\u00fcs evade los anticuerpos neutralizantes mediante una cavidad profunda que obstaculiza la respuesta inmunitaria del hu\u00e9sped,\u00a0resolviendo un enigma cient\u00edfico de casi una d\u00e9cada.<\/p>\n<p style=\"text-align: justify\">Transmitido principalmente por roedores,\u00a0el hantavir\u00fcs causa un s\u00edndrome pulmonar de elevada letalid\u00e4d.\u00a0A diferencia de otras variantes conocidas,\u00a0la cepa andina destaca por su capacidad de transmisi\u00f3n interhumana mediante contacto directo y prolongado,\u00a0por lo que el mapa estructural obtenido constituye una base fundamental para dise\u00f1ar herramientas de protecci\u00f3n global frente a este agente infeccios\u00f6.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>NOTI-AMERICA.COM | CHILE Un equipo multidisciplinario de cient\u00edficos del Albert Einstein College of Medicine,\u00a0el Institut Pasteur y LSU Health Shreveport logr\u00f3 descifrar la estructura molecular mediante la cual el hantavir\u00fcs andino se adhiere a&#46;&#46;&#46;<\/p>\n","protected":false},"author":133,"featured_media":97401,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"_acf_changed":false,"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"no","rop_publish_now_accounts":{"facebook_10219548024599422_1632221337088128":"","twitter_242054905_242054905":""},"rop_publish_now_history":[{"account":"twitter_242054905_242054905","service":"twitter","timestamp":1792704768,"status":"error"}],"rop_publish_now_status":"done","footnotes":""},"categories":[13],"tags":[],"class_list":["post-97400","post","type-post","status-publish","format-image","has-post-thumbnail","hentry","category-vida-y-salud","post_format-post-format-image"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.9 (Yoast SEO v28.7) - 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